Approved Use

EVENITY® is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk of fracture, (See More) or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well.

For women with postmenopausal osteoporosis at high risk for fracture

did you know?

Osteoporosis is referred to as a silent disease because you may not know you have it until you break a bone.

Up to 20% of bone loss happens in the first 5 to 7 years after menopause

2 out of 3 women with postmenopausal osteoporosis at high risk for fracture will break a bone in their lifetime

A bone fracture can be a warning sign of osteoporosis and should not be ignored

After an osteoporosis-related fracture, you’re 5x more likely to suffer another fracture within a year

Is it time for a DXA scan?

A DXA scan is a quick, painless, noninvasive procedure that measures bone density and provides a T-score to understand how at risk you are for a bone fracture. If you have been diagnosed with postmenopausal osteoporosis, your doctor may recommend a bone density scan every 1 to 2 years to monitor your progress on treatment.

Your T-score helps to determine the severity of your risk of breaking a bone.

Bone density T-score scale: Normal bone density to osteoporosis Bone density T-score scale: Normal bone density to osteoporosis

Normal bone density

Low bone density

Osteoporosis

A bone density T-score of -2.5 or lower is defined as osteoporosis. The lower the score, the greater your risk of fracture.

Know your risk

The more of the following risk factors you have, the higher your risk of breaking a bone.

  • T-score less than or equal to -2.5
  • Age 65 or older
  • Low body weight
  • Previous broken bone
  • History of falling
  • Excessive alcohol use (≥3 drinks/day)
  • Parent suffered a hip fracture
  • Cigarette smoking
  • Rheumatoid arthritis
  • Diabetes
  • Long-term steroid use such as prednisone

Know how different osteoporosis treatments work

There are two types of osteoporosis treatments—antiresorptives and anabolics. Each treatment type works differently, so take a look below to learn more.

OTHER TREATMENTS WORK ONE WAY

Some medications work to just build new bone, while other medications just slow down bone loss.

EVENITY® WORKS TWO WAYS

EVENITY is an anabolic treatment that’s unique because it’s the only one that works two ways by building new bone and helping to slow bone loss.

Important Safety Information

What is the most important information I should know about EVENITY?

EVENITY can cause serious side effects, including increased risk of having a heart attack, stroke, or death from a cardiovascular (heart or blood vessel) problem. Call your healthcare provider or get emergency help right away if you have any of these symptoms: symptoms of heart attack, which may include: chest pain or pressure; shortness of breath; feeling light-headed or dizzy; or symptoms of stroke, which may include: headache; numbness or weakness in face, arm, or legs; difficulty talking; changes in vision or loss of balance. Before you receive EVENITY, tell your healthcare provider if you have had a heart attack or stroke, especially if it has happened in the past year.

Do not receive EVENITY if you: have low blood calcium; or are allergic to romosozumab or any of the ingredients in EVENITY.

Before receiving EVENITY, tell your healthcare provider about all your medical conditions, including if you:

  • have a history of other heart or blood vessel problems
  • have low blood calcium
  • cannot take daily calcium and vitamin D
  • have kidney problems or are on kidney dialysis
  • plan to have dental surgery or teeth removed

What are the possible side effects of EVENITY?

EVENITY may cause serious side effects, including:

Serious allergic reactions have happened in people who receive EVENITY. Call your healthcare provider or go to the nearest emergency room right away if you have any symptoms of a serious allergic reaction including: rash; hives; swelling of the face, lips, mouth, tongue, or throat which may cause difficulty in swallowing or breathing.

Low calcium levels in your blood (hypocalcemia). EVENITY may lower the calcium levels in your blood. Your low blood calcium should be treated before you receive EVENITY. Call your healthcare provider if you have symptoms of low blood calcium such as: spasms, twitches, or cramps in your muscles; numbness or tingling in your fingers, toes or around your mouth.

Severe jaw bone problems (osteonecrosis) may occur. Your healthcare provider should examine your mouth before you start EVENITY and may tell you to see your dentist. Ask your healthcare provider or dentist about good mouth care.

Unusual thigh bone fractures. Symptoms of this type of fracture include new or unusual pain in your hip, groin, or thigh.

The most common side effects of EVENITY include joint pain and headaches.

These are not all the possible side effects of EVENITY. Call your doctor for medical advice about side effects.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Please see EVENITY full Prescribing Information, including Medication Guide.

Approved Use:

EVENITY is a prescription medicine used to treat osteoporosis in women after menopause who are at high risk of fracture, or cannot use another osteoporosis medicine or other osteoporosis medicines did not work well.

Important Safety Information

What is the most important information I should know about EVENITY?

EVENITY can cause serious side effects, including increased risk of having a heart attack, stroke, or death from a cardiovascular (heart or blood vessel) problem. Call your healthcare provider or get emergency help right away if you have any Read More